Obstet Gynecol Sci.  2013 Sep;56(5):341-344.

Ovarian metastasis from pulmonary adenocarcinoma

• Jung YE
• Lee JW
• Kim BG
• Bae DS

Abstract

Metastatic ovarian cancer is not an uncommon finding. Such tumors almost always originate from female genital tract, colon, stomach, or breast. Lung cancer is not a common origin of ovarian metastases. Of all metastatic ovarian tumors, approximately 0.3% arise from lung cancer. Ovarian torsion is not an uncommon finding, but ovarian torsion with cancer is rare. Here, we report a 44-year-old woman who was previously diagnosed with advanced stage lung cancer and who emergently visited our hospital for abdominal pain. An imaging work-up revealed, ovarian torsion and exploratory laparotomy was performed. Pathological examination led to the diagnosis ovarian metastasis from lung cancer. This is the first case of ovarian metastasis from lung cancer, ovarian torsion.

Keyword

Lung cancer; Metastatic ovarian cancer; Ovarian torsion

MeSH Terms

Abdominal Pain
Adenocarcinoma
Adult
Breast
Colon
Female
Humans
Laparotomy
Lung Neoplasms
Neoplasm Metastasis
Ovarian Neoplasms
Stomach

Figure

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  Fig. 1 Magnetic resonance imaging with 12 × 9.3 cm cystic and solid mass arising from the right adnexa as well as a torsion knob and hemorrhage, suggesting torsion of a cyst on the right ovary.

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  Fig. 2 (A) In gross finding, 12 × 10 cm of right ovarian tumor and cystic space showing a black hemorrhage and solid portion. (B) In microscopic finding, ovarian mass shows glandular structure and resemble the normal lung gland (H&E, ×40). (C) In high power field, tumor cells contain cuboidal to low-columnar cells with cytologic atypia, including hyperchromasia, pleomorphism and prominent nucleoli (H&E, ×200). (D) The tumor cells express TTF-1, which means that they metastasized from lung (TTF-1, ×200).

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