Nucl Med Mol Imaging.  2015 Jun;49(2):153-156. 10.1007/s13139-014-0311-3.

Precision of SPECT/CTAllows the Diagnosis of a Hidden Brodie's Abscess of the Talus in a Patient with Sickle Cell Disease

• Al-Jafar H
• Al-Shemmeri E
• Al-Shemmeri J
• Aytglu L
• Afzal U
• Al-Enizi S

• KMID: 2313263
• DOI: http://doi.org/10.1007/s13139-014-0311-3

Abstract

Brodie's abscess is a rare subacute osteomyelitis that can be found in sickle cell disease along with other bone complications. A 21-year-old female with sickle cell disease was presenting frequently to the medical casualty department for painful vasoocclusive crises and for persistent ankle pain and swelling.Hybrid imagingwith single-photon emission computed tomography-computed tomography (SPECT-CT) incidentally revealed Brodie's abscess in the talus bone of the ankle, causing persisting long-standing pain. SPECT-CT is a modern technology used to scan bone to detect both anatomical and functional abnormalities with high specificity. Brodie's abscess is a rare bone inflammation that could be a hidden cause of pain and infection in sickle cell disease. Although rare, this lesion requires more attention in patients with sickle cell disease because their immunocompromised status renders them prone to this infection.

Keyword

Sickle cell disease; Brodie's abscess; SPECT-CT

MeSH Terms

Abscess*
Anemia, Sickle Cell*
Ankle
Diagnosis*
Female
Humans
Osteitis
Osteomyelitis
Sensitivity and Specificity
Talus*
Young Adult