Nucl Med Mol Imaging.  2015 Mar;49(1):65-68. 10.1007/s13139-014-0302-4.

Unexpected Second Primary Malignancies Detected by F-18 FDG PET/CT During Follow-up for Primary Malignancy: Two Case Reports

Affiliations
  • 1Department of Nuclear Medicine, Research Institute and Hospital, National Cancer Center, Korea, 323 Ilsan-ro, Ilsandong-gu, Goyang, Gyeonggi 410-769, Republic of Korea. les-silver@hanmail.net

Abstract

As the survival rate of cancer patients has increased over the last few decades, the risk of cancer survivors developing second primary malignancies has gained attention. We report two rare cases of second primary hematologic malignancy detected by 18F-fluorodeoxyglucose (F-18 FDG) positron emission tomography/computed tomography (PET/CT) during follow-up for primary solid malignancies. Acute lymphoblastic leukemia developed in a breast cancer patient and non-Hodgkin lymphoma in an anal cancer patient. F-18 FDG PET/CT findings led to the diagnosis of unexpected second primary hematologic malignancy in cancer survivors in these two cases.

Keyword

F-18 fluorodeoxyglucose; Positron emission tomography; Second primary malignancy; Hematologic malignancy

MeSH Terms

Anus Neoplasms
Breast Neoplasms
Diagnosis
Electrons
Follow-Up Studies*
Hematologic Neoplasms
Humans
Lymphoma, Non-Hodgkin
Positron-Emission Tomography
Positron-Emission Tomography and Computed Tomography*
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Survival Rate
Survivors
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