Nucl Med Mol Imaging.
2015 Mar;49(1):52-56. 10.1007/s13139-014-0295-z.
Usefulness of 131I-SPECT/CT and 18F-FDG PET/CT in Evaluating Successful 131I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii
- Affiliations
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- 1Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul, Korea.
- 2Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehangno, Jongro-gu, Seoul 110-744, Korea. jkchung@snu.ac.kr
- 3Department of Nuclear Medicine, Anyang SAM Hospital, Gyeonggi-do, Korea.
- 4Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Korea.
- 5Department of Pathology, Seoul National University Hospital, Seoul, Korea.
- 6Department of Oncology, GSAM Hosptial, Gyeonggi-do, Korea.
- KMID: 2313245
- DOI: http://doi.org/10.1007/s13139-014-0295-z
Abstract
- Metastatic struma ovarii is an extremely rare disease, and the treatment of choice has not been established. Here, we introduce the case of a 36-year-old female pregnant patient with metastatic struma ovarii. Initial treatment was an exploratory laparotomy to remove multiple peritoneal masses. After delivery, a total thyroidectomy was done for the further 131I-therapy. 131I-SPECT/CT and 18F-FDG PET/CT showed multiple hepatic metastases and extensive peritoneal seeding nodules. Multiple 131I and retinoic acid combination therapies were performed, resulting in marked improvement. 131I-SPECT/CT and 18F-FDG PET/CT were quite useful for evaluating the biologic characteristics of the metastases.
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