Nucl Med Mol Imaging.
2009 Aug;43(4):361-362.
A Neurofibroma Confused with Sarcomatous Transformation on F-18 FDG PET/CT in Neurofibromatosis-1
- Affiliations
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- 1Department of Nuclear Medicine, Wonkwang University College of Medicine, Iksan, Korea. nmbach@wonkwang.ac.kr
- 2Department of Plastic and Reconstructive Surgery, Wonkwang University College of Medicine, Iksan, Korea.
- 3Department of Physical Medicine and Rehabilitation, Wonkwang University College of Medicine, Iksan, Korea.
- 4Department of Pathology, Wonkwang University College of Medicine, Iksan, Korea.
- 5Department of Urology, Wonkwang University College of Medicine, Iksan, Korea.
- 6Department of Institute of Wonkwang Medical Science, Wonkwang University College of Medicine, Iksan, Korea.
Abstract
- We present a patient with high 18F-fluorodeoxyglucose (FDG) uptake detected in a neurofibroma that was confused with sarcomatous transformation on a positron emission tomography/computed tomography (PET/CT) scan. A 39-year-old male patient with a 20-year history of neurofibromatosis-1 (NF-1) performed FDG PET/CT scan for the evaluation of lesions with sarcomatous transformation. The FDG PET/CT images demonstrated varying degrees of increased FDG uptake in the multiple nodules throughout whole body. The left pelvic mass with the highest FDG uptake had a maximum standardized uptake values (maxSUV) 5.0 and surgical resection was performed. Histological analysis confirmed the presence of a benign neurofibroma infiltrated with inflammatory cells.
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