Mycobiology.
2010 Dec;38(4):328-330.
In Vitro Antifungal Activity of Equol against Candida albicans
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- 1Department of Cell Biology, College of Medicine, Konyang University, Daejeon 302-718, Korea. hychee@konyang.ac.kr
Abstract
- In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 microM, respectively. Two separate viability assays found that equol changed the integrity of the C. albicans cell membrane, possibly by formation of membrane lesions. Scanning electron microscopy demonstrated ultrastructural changes.
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