Korean J Med Mycol.  2009 Sep;14(3):127-132.

Antifungal Activity of the Essential oil from Eucalyptus and Eucapytol against Candida albicans

• Seong I

Abstract

BACKGROUND
Candida albicans is a member of the normal flora of the skin, mucous membranes and gastrointestinal tract. Vaginal candidiasis remains a significant problem in women
OBJECTIVE
The purpose of this study was to develop the antifungal agent from the medicinal herbs traditionally used in Korea. Method: In this study, the essential oil of eucalyptus, cedar wood, clary sage, orange sweet and eucapytol were examined for antifungal activities against C. albicans.
RESULTS
1. Eucalyptus essential oil and eucapytol showed antifungal activity against C. albicans. 2. Minimal inhibitory concentration (MIC) of Eucapytol against eight strains and standard strains was 12.5 microliter/ml and 6.25 microliter/ml against two strains. 3. MIC of eucapytol was 25 microliter/ml against eight strains and 50 microliter/ml against two.
CONCLUSION
Eucalyptus essential oil and eucalytol could be a candidate for a new antifungal agent for candidiasis and other fungal diseases.

Keyword

Eucalyptus oil; Eucapytol; Antifungal activity; Candida albicans

MeSH Terms

Candida
Candida albicans
Candidiasis
Citrus sinensis
Eucalyptus
Gastrointestinal Tract
Mucous Membrane
Plants, Medicinal
Skin
Wood