Korean J Urol.  2009 Mar;50(3):300-302.

Testicular Sertoli Cell Tumor in an Adult

Affiliations
  • 1Department of Urology, Pusan National University Yangsan Hospital, Pusan University College of Medicine, Busan, Korea. lsd@pusan.ac.kr

Abstract

Sertoli cell tumors of the testis are very rare and are usually benign. Here we report a case of a Sertoli cell tumor of the testis in a 46-year-old man. His chief complaint was a painless, palpable testicular mass that he had for 4 years. Serum levels of tumor markers were within normal limits. Testicular ultrasonography showed a 1.5 cm sized well-demarcated nonhomogeneous echogenic mass in the left testis. Chest x-ray and abdominopelvic CT showed no metastasis. Radical orchiectomy was performed. Histopathology showed a Sertoli cell tumor with no evidence of malignancy.

Keyword

Sertoli cell tumor; Testis

MeSH Terms

Adult
Humans
Middle Aged
Neoplasm Metastasis
Orchiectomy
Sertoli Cell Tumor
Testis
Thorax
Biomarkers, Tumor

Figure

  • Fig. 1 Testicular ultrasonogram showing a 1.5×1.5 cm well-defined heterogeneous echogenic mass.

  • Fig. 2 Microscopic findings of the specimen showing tubular and focal solid growth of the tumor cell (arrow head) surrounded by stromal elements (H&E, ×200).

  • Fig. 3 Immunohistochemical staining of specimens showing that tumor cells were positive for cytokeratin (arrow)(A) and vimentin (arrow head)(B) (×100).


Reference

1. Richie JP, Steele GS. Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Neoplasms of the testis. Campbell's urology. 2007. 9th ed. Philadelphia: Saunders;893–935.
2. Jeong CS, Seo IY, Rim JS. Malignant Sertoli cell tumor of testis. Korean J Urol. 2003. 44:1064–1066.
3. Kim YH. Malignant Sertoli cell tumor of the testis in adult. J Soonchunhyang Med Coll. 2004. 10:1373–1376.
4. Jung SI, Min KD, Kwon DD, Oh BR, Ryu SB, Park YI, et al. Sertoli cell tumor of the testis in a young child. Korean J Urol. 2001. 42:675–677.
5. Young RH, Koelliker DD, Scully RE. Sertoli cell tumors of the testis, not otherwise specified: a clinicopathologic analysis of 60 cases. Am J Surg Pathol. 1998. 22:709–721.
6. Kratzer SS, Ulbright TM, Talerman A, Srigley JR, Roth LM, Wahle GR, et al. Large cell calcifying Sertoli cell tumor of the testis: contrasting features of six malignant and six benign tumors and a review of the literature. Am J Surg Pathol. 1997. 21:1271–1280.
7. Zukerberg LR, Young RH, Scully RE. Sclerosing Sertoli cell tumor of the testis. A report of 10 cases. Am J Surg Pathol. 1991. 15:829–834.
8. Godec CJ. Malignant Sertoli cell tumor of testicle. Urology. 1985. 26:185–188.
9. Comperat E, Tissier F, Vieillefond A. Late metastasis after a testicular Sertoli cell tumor. Ann Pathol. 2004. 24:45–46.
10. Kolon TF, Hochman HI. Malignant Sertoli cell tumor in a prepubescent boy. J Urol. 1997. 158:608–609.
Full Text Links
  • KJU
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr