Endocrinol Metab.  2016 Jun;31(2):343-344. 10.3803/EnM.2016.31.2.343.

18F-FDG PET/CT-Guided Clinical Management of the Rare Aggressive "Columnar-Cell" Variant of Papillary Thyroid Cancer

• Vadrucci M
• Serio G
• Baroli A

• KMID: 2308866
• DOI: http://doi.org/10.3803/EnM.2016.31.2.343

Abstract

No abstract available.

MeSH Terms

Fluorodeoxyglucose F18*
Thyroid Gland*
Thyroid Neoplasms*
Fluorodeoxyglucose F18

Figure

• 

  Fig. 1 (A) Preoperative 18-fluoro-2-deoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) scan showing the primary tumor in the right thyroid lobe and gross metastatic right neck lymph nodes. (B) Post-operative 131 whole body scan showing an iodine-avid focus in the thyroid bed. (C) Restaging 18F-FDG-PET/CT scan detected disease recurrence in the left subcutaneous nodules and in the lymph nodes of the central neck compartment and right supraclavicular fossa (arrow). (D) 18F-FDG-PET/CT demonstrating complete disease remission 1 year after salvage neck surgery and external beam radiotherapy. (E) Histological examination of the right thyroid lobe showing tumor cells with elongated nuclei and multiple pseudo-stratifications suggestive of the columnar-cell variant of papillary thyroid cancer (H&E stain, ×200). (F) Subcutaneous metastasis of columnar-cell papillary thyroid cancer (H&E stain, ×200).

Reference

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3. Salvatori M, Biondi B, Rufini V. Imaging in endocrinology: 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/ computed tomography in differentiated thyroid carcinoma: clinical indications and controversies in diagnosis and follow-up. Eur J Endocrinol. 2015; 173:R115–R130.