Gastrointest Interv.  2016 Mar;5(1):67-71. 10.18528/gii150029.

Lidocaine spray on an endoscope immediately before insertion improves patient tolerance to endoscopy: A single center, clinical observational study

Affiliations
  • 1Department of Gastroenterology, Division of Medicine, Sheikh Khalifa Specialty Hospital, Ras Al Khaimah, United Arab Emirates. doctorhyo@gmail.com
  • 2Digestive Disease Center, Department of Internal Medicine, Cheju Halla General Hospital, Jeju, Korea.
  • 3Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Kyungpook National University College of Medicine, Daegu, Korea.
  • 4Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 5Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Abstract

BACKGROUND
Topical pharyngeal anesthesia reduces discomfort during upper gastrointestinal endoscopy (UGIE) but may not increase tolerance to the procedure. This case-control study was performed to assess whether lidocaine spray on the endoscope in addition to pharyngeal anesthesia improves patient tolerance to endoscopy we performed.
METHODS
Patients who underwent UGIE were assigned to either the case group where the endoscope was treated with 2 sprays of 10% lidocaine before insertion or the control group given only conventional pharyngeal anesthesia. And we compared the frequency of belching and retching during endoscopy.
RESULTS
Among 497 eligible patients, 262 were assigned to the case group and 235 to the control group. There were significant differences between the two groups in belching (odds ratio [OR] = 0.15, 95% confidence interval [CI] = 0.09-0.24, P < 0.01) and retching (OR = 0.22, 95% CI = 0.15-0.34, P = 0.01) during endoscopy using multivariate analysis. Younger patients (OR = 0.96, 95% CI = 0.94-0.98, P < 0.01) and female patients (OR = 2.16, 95% CI = 1.40-3.33, P = 0.01) had belching more frequently than older patients and male patients, respectively. Retching was more frequent in sedated patients (OR = 0.39, 95% CI = 0.25-0.61, P = 0.01) and those with gastro-esophageal reflux disease (OR = 1.48, 95% CI = 1.00-2.21, P = 0.06).
CONCLUSIONS
Use of lidocaine spray on the endoscope improves patient tolerance during UGIE compared to only conventional pharyngeal anesthesia.

Keyword

Belching; Endoscopy, gastrointestinal; Gagging; Lidocaine; Pharyngeal anesthesia

MeSH Terms

Anesthesia
Case-Control Studies
Endoscopes*
Endoscopy*
Endoscopy, Gastrointestinal
Eructation
Female
Gagging
Gastroesophageal Reflux
Humans
Lidocaine*
Male
Multivariate Analysis
Observational Study*
Lidocaine
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