J Dent Anesth Pain Med.  2016 Mar;16(1):55-59. 10.17245/jdapm.2016.16.1.55.

Dexmedetomidine intravenous sedation using a patient-controlled sedation infusion pump: a case report

• Chi SI
• Kim HJ
• Seo KS

• KMID: 2308766
• DOI: http://doi.org/10.17245/jdapm.2016.16.1.55

Abstract

Dental treatment under sedation requires various sedation depths depending on the invasiveness of the procedure and patient drug sensitivity. Inappropriate sedation depth may cause patient discomfort or endangerment. For these reasons, patient-controlled sedation (PCS) pumps are commonly used. Patients are able to control the sedation depths themselves by pushing the demand button after the practitioner sets up the bolus dose and lock-out time. Dexmedetomidine is an α-2 adrenoreceptor agonist with sedative, analgesic, and anxiolytic properties. It has been widely used for sedation for its minimal respiratory depression; however, there are few studies on PCS using dexmedetomidine. This study assessed the applicability of dexmedetomidine to PCS.

Keyword

Conscious sedation; Dexmedetomidine; Patient-controlled sedation

MeSH Terms

Conscious Sedation
Dexmedetomidine*
Humans
Infusion Pumps*
Respiratory Insufficiency
Dexmedetomidine

Figure

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  Fig. 1 Upper Left: Patient with nasal cannula and Bispectral index sensor, with 3 L/min O2 supplied through the nasal cannula. Upper right: Demand button on patient's hand, with a Velcro belt that prevents the patient from missing the button; Lower left: Upon pressing the button, the patient is administered dexmedetomidine; Lower right: If the patient presses the button more than once within 1 min, the lock-out time is activated.

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  Fig. 2 Patient vital signs and demand button presses.

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  Fig. 3 Bispectral index and calculated plasma concentrations of dexmedetomidine [20]. BIS: Bispectral index, Cp: plasma concentration of dexmedetomidine

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