Kosin Med J.  2015 Jun;30(1):69-72. 10.7180/kmj.2015.30.1.69.

A Case of Focal Segmental Glomerulosclerosis in Turner Syndrome

• Han AR
• Lee YK
• Jung HY
• Park JH
• Noh JW
• Nam ES

• KMID: 2308539
• DOI: http://doi.org/10.7180/kmj.2015.30.1.69

Abstract

Turner syndrome is usually accompanied with various anomalies. Congenital urological and renal abnormalities are often associated with this syndrome. The occurrence of glomerulonephritis is uncommon. An 18-year-old woman showed fatigue and profound proteinuria. She had been diagnosed with Turner syndrome in her age of 15. The kidney biopsy specimen examined by light microscopy, immunofluorescence and electron microscopic examination revealed focal segmental glomerulosclerosis. This is the first case report of focal segmental glomerulosclerosis in turner syndrome in South Korea.

Keyword

Focal Segmental; Glomerulosclerosis; Proteinuria; Turner syndrome

MeSH Terms

Adolescent
Biopsy
Fatigue
Female
Glomerulonephritis
Glomerulosclerosis, Focal Segmental*
Humans
Kidney
Korea
Microscopy, Fluorescence
Proteinuria
Turner Syndrome*

Figure

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  Figure 1. Jone-silver stain reveals segmental sclerosis in two glomeruli and tubular atrophy and interstitial foam cells(A, x200). Electron microscopy displays diffuse effacement of foot processes. There is no electron dense material deposit(B).

Reference

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