Korean J Women Health Nurs.  2013 Dec;19(4):201-210. 10.4069/kjwhn.2013.19.4.201.

Characteristics and Quality of Life in Gynecologic Cancer Patients with Chemotherapy-induced Peripheral Neuropathy

Affiliations
  • 1Asan Medical Center, Seoul, Korea.
  • 2Department of Nursing, University of Ulsan, Ulsan, Korea. jhnho@ulsan.ac.kr

Abstract

PURPOSE
The purpose of this study was to identify chemotherapy induced peripheral neuropathy, quality of life of patients with gynecologic cancer.
METHODS
This was a cross-sectional survey design. We collected 130 patients with gynecologic cancer. They complete a self reported questionnaire including items related neuropathy and quality of life (FACT-GOG/Ntx subscale, FACT-G scale).
RESULTS
The neuropathy score was 14.3+/-7.9. The quality of life score was 64.8+/-16.4. The neuropathy induced significant difference according to diabetic status, difficulties in performing household chores and willing to discontinuity of chemotherapy. And duration of cancer diagnosis, neuropathy, number of total chemo agent associated with quality of life. There was a negative correlation between number of total chemo agent and quality of life. Neuropathy independently affected quality of life.
CONCLUSION
Chemotherapy induced peripheral neuropathy of patients with gynecologic cancer adversely affected women's quality of life and activities of daily living. To improve patient's quality of life, it is important that accurate assess and appropriately manage neuropathy in patients with gynecologic cancer.

Keyword

Gynecologic neoplasm; Chemotherapy induced peripheral neuropathy; Quality of life

MeSH Terms

Activities of Daily Living
Cross-Sectional Studies
Diagnosis
Drug Therapy
Family Characteristics
Female
Genital Neoplasms, Female
Humans
Peripheral Nervous System Diseases*
Quality of Life*
Surveys and Questionnaires
Self Report
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