The Effect of Cholecystectomy on the Motility of the Sphincter of Oddi

Ryu, Kwon Ho; Lee, Joon Seong; Cheon, Young Koog; Song, Hae Jung; Kim, Yeon Soo; Eun, Soo Hoon; Kim, Sang Gyun; Jang, Jae Young; Hong, Su Jin; Kim, Young Seok; Moon, Jong Ho; Cho, Young Deok; Lee, Moon Sung; Shim, Chan Sup; Kim, Boo Sung

Abstract

BACKGROUND/AIMS: The perendoscopic manometry of the sphincter of Oddi (SO) may not represent the overall SO motility. To assess the effect of cholecystectomy on SO motility, SO manometry was performed via the percutaneous transhepatic route.
METHODS
Percutaneous transhepatic SO manometry was performed in 26 patients with IHD stones. Seventeen patients had undergone cholecystectomy, and the others had not (the control group). We performed antroduodenal manometry simultaneously in 4 patients.
RESULTS
There was no significant difference of basal pressures, the mean frequency of phasic contractions, and the distribution of phasic contraction types of SO between the cholecystectomy group and the control group. Forty occasions of high frequency type phasic contractions were observed in 18 patients. The mean interval of high frequency contractions in the cholecystectomy group was shorter than that in the control group (40.1+/-21.9 vs. 69.9+/-19.0 min, respectively, p<0.05), and the mean duration of high frequency contractions in the cholecystectomy group was longer than that in the control group (6.1+/-2.1 vs. 5.0+/-1.6 min, respectively, p<0.05). Twenty high frequency contractions of SO coincided with duodenal MMC III on the antroduodenal manometry.
CONCLUSIONS
A longer duration and shorter intervals of high frequency contractions were observed in the cholecystectomy group. High frequency contractions of SO were observed periodically without biliary pain and these coincided with duodenal MMC III.