Korean J Neurogastroenterol Motil.  2009 Jun;15(1):31-37.

Is there any Difference in the Esophageal Motor Parameters of High Resolution Manometry between the Supine and Sitting Positions?

• Lee JS
• Park MI
• Moon W
• Kim GM
• Park SJ
• Kim KJ
• Park EH
• Shin EK
• Yim DH
• Choi PR
• Park DY
• Park CB

Abstract

BACKGROUND/AIMS: High-resolution manometry (HRM) is a new methodology that can be done at any position. The aim of this study was to determine whether the body position affects the esophageal manometric parameters.
METHODS
Twenty nine subjects (15 males and 14 females, age: 53.1+/-13.2) were studied with a 36-channel HRM assembly. The subjects performed ten 5-mL water-swallows in the sitting position. At 15 minutes, the same study was done in the supine position. The basal mean LES pressure and the UES pressure, the mean wave amplitude, the velocity and the deglutitive relaxation were analyzed automatically using ManoViewTM. The Pressurization front velocity (PFV) and distal contractile integral (DCI) were manually calculated using the Smart Mouse tool in ManoViewTM. We used the Chicago classification1 for the diagnosis.
RESULTS
The mean manometric parameters in the sitting and supine positions were the basal LES pressure (20.9+/-7.0 mmHg vs 22.4+/-8.3 mmHg, respectively, p=0.28), the basal UES pressure (51.0+/-30.2 mmHg vs 49.7+/-17.2 mmHg, respectively, p=0.11), the wave amplitude (64.7+/-29.0 mmHg vs 73.9+/-41.0 mmHg, respectively, p=0.19), velocity (5.4+/-4.5 cm/s vs 5.8+/-5.3 cm/s, respectively, p=0.91), the PFV (4.2+/-1.2 cm/sec vs 4.3+/-0.9, respectively, p=0.70), and the deglutitive relaxation (9.2+/-4.6 mmHg vs 11.2+/-4.3, respectively p=0.23). Only the DCI was significantly increased in the supine position (2625.6+/-1265.9 mmHg.s.cm vs 3426.4+/-1542.6 mmHg.s.cm, respectively, p<0.01). A different final diagnosis was noted in 7 subjects (24.1%) at each position.
CONCLUSIONS
The patient position during HRM study may affect the esophageal motor parameters and the final diagnosis.

Keyword

High-resolution manometry; Esophageal motor parameters; Esophageal motor function

MeSH Terms

Animals
Chicago
Female
Humans
Male
Manometry
Mice
Relaxation
Supine Position