Korean J Nephrol.
1999 Nov;18(6):989-993.
A Case of Spontaneous Bacterial Peritonitis as the Presenting Feature in a
Patient with Nephrotic Syndrome
Abstract
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Although spontaneous bacterial peritonitis is a frequent complication in the childhood
nephrotic syndrome, it is very rare in adults with nephrotic syndrome. It frequently
develops when the patients are either in relapse or receiving steroid therapy at the
time peritonitis is diagnosed. We report an unusual case of a spontaneous bacterial
peritonitis as the presenting feature in a 15-year-old male patient with nephrotic syndrome.
He presented with diffuse abdominal pain and distension for 15 days. Abdominal paracentesis
revealed the diagnostic laboratory findings of peritonitis, and the bacterial culture of the
ascites showed a mixed growth of Escherichia coli and Pseudomonas aeruzinosa. His serum
albu- min level was 1.6gldL and the amount of 24 hours proteinuria was 21.0g/day. Although
he was treated with adequate antibiotics for 3 weeks, the peritonitis was more aggravated.
We decided to insert a catheter into the peritoneal cavity for continuous drainage of the
intractable ascites. Two weeks after drainage, the peritonitis improved as the peritonitis
subsided, the proteinuria disappeared completely without a steroid therapy. Six months after
spontaneous remission, the proteinuria have recurred, and the kidney biopsy then showed focal
segmental glomerulorsclerosis.