Korean J Med.
1999 Feb;56(2):235-239.
A Case of CD5 Negative B-Cell Chronic Lymphocytic Leukemia
- Affiliations
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- 1Department of Internal Medicine, Pusan Veterans Hospital, Korea.
- 2Department of Clinical Pathology, Pusan Veterans Hospital, Korea.
- 3Department of Anatomical Pathology, Pusan Veterans Hospital, Korea.
- 4Department of Clinical Patholog Pusan Paik hospital, College of Medicine, In Je University, Pusan, Korea.
Abstract
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A 67-year-old male visited Pusan Veterans Hospital due to general weakness and weight loss for
6 months. Physical examination showed non-tender 4 finger breaths sized splenomegaly and both
inguinal and cervical lymphadenopathy. The white blood cell count was 25,300/uL with 91%
morphologically mature lymphocytes. Bone marrow aspirate revealed hypercellularity with 74.5%
lymphocytes morphologically similar to peripheral lymphocytes. The immunophenotpying study of
lymphocytes displayed the phenotype of CD19(+), CD20(+), HLA-DR(+), sIg(+) but CD5(-).
We concluded that this patients's diagnosis is CD 5 negative B-cell chronic lymphocytic leukemia.