Korean J Med.
1999 Jun;56(6):771-776.
A Case of Metastatic Carcinoma en Cuirasse and Nodular Carcinoma from Gastric Carcinoma
- Affiliations
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- 1Department of Internal Medicine, Kwangju Veterans Hospital, Kwangju, Korea.
- 2Department of Dermatology, Kwangju Veterans Hospital, Kwangju, Korea.
- 3Department of Pathology, Kwangju Veterans Hospital, Kwangju, Korea.
Abstract
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Cutaneous metastases from gastric carcinoma are uncommon. The frequency of metastses to the
skin from gastric carcinoma have ranged from 0.3% to 0.4%. Carcinoma en cuirasse, first
described by Velpeau in 1838, is marked sclerodermatous change and characterized by a difffuse
morphea-like induration of the skin and represents a rare manifestations of breast carcinoma
metastatic to the chest wall. It is vary rarely seen in lung, stomach, kidney and other
metastasizing malignancies.
We report a case of carcinoma en cuirase and nodular carcinoma from gastric carcinoma in
a 36-year-old male who complained chiefly of multiple cutaneous nodules. He had mixed lesions
of an erythematous morphea-like induration on the neck and multiple erythematous nodules on
the chest and abdomen. Gastroscopy finding showed a Borrmann type IV advanced gastric carcinoma.
Histopathologic examination of skin and stomach showed atypical cells with pleomorpic,
hyperchromatic nuclei and scanty, eosinophilic cytoplasm, which are consistent with poorly
differentiated adenocarcinoma. Immunohistochemical stainings showed positive reaction for
cytokeratin. He died three months after the appearance of cutaneous lesions.