Korean J Med.  1999 Jun;56(6):771-776.

A Case of Metastatic Carcinoma en Cuirasse and Nodular Carcinoma from Gastric Carcinoma

Affiliations
  • 1Department of Internal Medicine, Kwangju Veterans Hospital, Kwangju, Korea.
  • 2Department of Dermatology, Kwangju Veterans Hospital, Kwangju, Korea.
  • 3Department of Pathology, Kwangju Veterans Hospital, Kwangju, Korea.

Abstract

Cutaneous metastases from gastric carcinoma are uncommon. The frequency of metastses to the skin from gastric carcinoma have ranged from 0.3% to 0.4%. Carcinoma en cuirasse, first described by Velpeau in 1838, is marked sclerodermatous change and characterized by a difffuse morphea-like induration of the skin and represents a rare manifestations of breast carcinoma metastatic to the chest wall. It is vary rarely seen in lung, stomach, kidney and other metastasizing malignancies. We report a case of carcinoma en cuirase and nodular carcinoma from gastric carcinoma in a 36-year-old male who complained chiefly of multiple cutaneous nodules. He had mixed lesions of an erythematous morphea-like induration on the neck and multiple erythematous nodules on the chest and abdomen. Gastroscopy finding showed a Borrmann type IV advanced gastric carcinoma. Histopathologic examination of skin and stomach showed atypical cells with pleomorpic, hyperchromatic nuclei and scanty, eosinophilic cytoplasm, which are consistent with poorly differentiated adenocarcinoma. Immunohistochemical stainings showed positive reaction for cytokeratin. He died three months after the appearance of cutaneous lesions.

Keyword

Cutaneous metastases; Carcinoma en cuirasse; Gastric carcinoma

MeSH Terms

Abdomen
Adenocarcinoma
Adult
Breast Neoplasms
Cytoplasm
Eosinophils
Gastroscopy
Humans
Keratins
Kidney
Lung
Male
Neck
Neoplasm Metastasis
Skin
Stomach
Thoracic Wall
Thorax
Keratins
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