Korean J Med.  2007 Aug;73(2):223-227.

A case of cardiac malignant fibrous histiocytoma treated by cardiac autotransplantation

Affiliations
  • 1Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. oncopark@smc.samsung.com
  • 2Department of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 3Department of Thoracic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Primary cardiac tumors are rare findings and they are mostly benign. Malignant primary cardiac tumors make up 25% of the primary cardiac tumors and most of them are sarcomas. Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in late adulthood, and it is an extremely rare sub-type of cardiac sarcoma. It is known that MFH displays a poor clinical course with complete resection being the most important prognostic factor for survival. We described here the case of a malignant fibrous histiocytoma of the heart in a 54-year-old woman who presented with dyspnea. The tumor was treated by mass excision via cardiac explantation and autotransplantation followed by adjuvant chemotherapy. This is the first report of cardiac autotransplantation in Korea.

Keyword

Malignant fibrous histiocytoma; Heart neoplasm; Autologous transplantation

MeSH Terms

Autografts*
Chemotherapy, Adjuvant
Dyspnea
Female
Heart
Heart Neoplasms
Histiocytoma, Malignant Fibrous*
Humans
Korea
Middle Aged
Sarcoma
Transplantation, Autologous
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