Korean J Med.
2009 Apr;76(4):506-509.
A case of acinar cell carcinoma of the pancreas
- Affiliations
-
- 1Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea. stemcell@hanafos.com
- 2Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.
- 3Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.
Abstract
- Acinar cell carcinoma of the pancreas is a rare tumor that constitutes 1~2% of all pancreatic cancers. The clinical and radiologic findings are inconclusive when diagnosing this disease. Acinar cell carcinoma progresses rapidly and metastasizes early, resulting in a poor prognosis. A 41-year-old man was admitted for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography (PET)-CT showed a splenic mass involving the pancreatic tail with increased 18F-fluorodeoxyglucose (18F-FDG) uptake. A primary radical distal pancreatectomy and splenectomy were carried out. The pathology revealed acinar cell carcinoma of the pancreas. Three months later, a gastric recurrence was detected and a total gastrectomy was performed. Four months later, multiple hepatic metastases were found and a left hepatectomy was carried out. During treatment with capecitabine, no evidence of tumor progression was observed for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma that did not progress for 14 months with capecitabine treatment.
