Korean J Med.
2009 Dec;77(6):780-786.
Metastatic collecting duct (Bellini duct) carcinoma: A case report
- Affiliations
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- 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. koyoonho@catholic.ac.kr
- 2Department of Radiology, The Catholic University of Korea College of Medicine, Seoul, Korea.
- 3Department of Hospital Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.
Abstract
- Renal cell carcinoma accounts for 2.6% of all cancer, and most renal cell carcinoma has a clear cell origin. Bellini duct carcinoma, which arises from collecting duct cells (Bellini cells), is a rare type of renal cell carcinoma, constituting less than 1% of all renal cell carcinoma. The prognosis of Bellini duct carcinoma is very poor, and more than 60% of the patients die within 2 years of diagnosis. There is no consensus regarding the optimal treatment. We report a case of Bellini duct carcinoma in a 53-year-old male with multiple lung and liver metastases. The patient was treated with eight cycles of M-VAC (methotrexate, vincristine, doxorubicin, and cisplatin) combination chemotherapy. The patient currently shows a radiological partial response without disease progression 10 months after the chemotherapy.