Korean J Lab Med.  2003 Apr;23(2):88-91.

Comparison of the Indocyanine Green Clearance Test Using Conventional Blood Sampling and Finger Monitoring Methods

• Kim S
• Park R
• Lee KR
• Kim JH
• Kwon OH

Abstract

BACKGROUND
The indocyanine green (ICG) finger monitoring method is a newly developed noninvasive method for the ICG clearance test. This study was performed to determine its clinical usefulness compared with the conventional blood sampling method. METHODS: The ICG clearance test was performed on 270 patients using both the conventional blood sampling method and the finger monitoring method simultaneously. The plasma disappearance rate of the ICG and the 15-minute retention ratio (ICG R15) were analyzed and compared with the conventional blood sampling method. RESULTS: The plasma disappearance rate using the finger monitoring method was slightly lower than that of the conventional blood sampling method with good correlation (r=0.840, P<0.001). ICG R15 using finger monitoring method was slightly higher than that of the conventional blood sampling method with good correlation (r=0.839, P<0.001). CONCLUSIONS: As there was a good correlation between the conventional blood sampling method and the finger monitoring method, the latter method seemed to be clinically useful due to its convenience and accuracy.

Keyword

ICG clearance test; Finger monitoring method; Plasma disappearance rate; 15-minute retention ratio

MeSH Terms

Fingers*
Humans
Indocyanine Green*
Plasma
Indocyanine Green