Korean J Gastrointest Endosc.  2001 Aug;23(2):109-112.

A Case of Stricture of Second Portion of Duodemum Induced by Chronic Use of Nonsteroidal Anti-inflammatory Drug in Patient with Ankylosing Spondylitis and Rheumathoid Arthritis: A case report

• Ji JS
• Chung HW
• Lim DJ
• Paik CN
• Noh CH
• Park SH
• Min DJ
• Kim JI
• Han JY
• Kim JK
• Choi GY
• Chung IS
• Chung KW
• Sun HS

Abstract

In endoscopic clinical research studies of patients who take NSAIDs, 10% to 20% of patients develop gastric ulcers and 4% to 10% develop duodenal ulcers. Ulcers associated with chronic NSAIDs use are typically painless and are located in the prepyloric region of the stomach. These characteristics make NSAIDs potential causes of gastric outlet obstruction. There were multiple cases of single or multiple strictures that were found in the esophagus, small bowel and colon. Most of duodenal strictures were confined to bulbar area. Only one case of duodenal second portion diaphragmlike stricture was reported in association with acetylsalicylic acid. We experienced one case of chronic NSAIDs induced duodenal 2nd portion stricture in ankylosing spondylitis and rhemathoid arthritis patient and reported with a review of literature.

Keyword

Duodenal stricture; NSAIDs

MeSH Terms

Anti-Inflammatory Agents, Non-Steroidal
Arthritis*
Aspirin
Colon
Constriction, Pathologic*
Duodenal Ulcer
Esophagus
Gastric Outlet Obstruction
Humans
Spondylitis, Ankylosing*
Stomach
Stomach Ulcer
Ulcer
Anti-Inflammatory Agents, Non-Steroidal
Aspirin