Korean J Gastrointest Endosc.
2009 Jul;39(1):42-45.
A Case of a Duodenal Gastrointestinal Stromal Tumor with a Bleeding Ulcer
- Affiliations
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- 1Department of Internal Medicine, Kwandong University College of Medicine, Goyang, Korea. chg21@kd.ac.kr
- 2Department of Surgery, Kwandong University College of Medicine, Goyang, Korea.
- 3Department of Pathology, Kwandong University College of Medicine, Goyang, Korea.
Abstract
- Duodenal gastrointestinal stromal tumors (GISTs) are relatively rare tumors that commonly present with gastrointestinal bleeding. Evaluation with endoscopic ultrasonography (EUS) is a useful technique for the differential diagnosis of GISTs from other submucosal tumors. A 58-year-old man presented with melena and anemia. An esophago-gastroduodenoscopy showed the presence of a submucosal tumor in the second portion of the duodenum with central ulceration and a flat spot. EUS showed the presence of a suspicious malignant GIST that originated from the proper muscle layer, which was successfully resected. We report a case of a duodenal GIST with a bleeding ulcer. Positive reactivity for CD117 and S-100 was demonstrated by immunohistochemical staining.