Korean J Gastroenterol.
1999 Jul;34(1):136-141.
A Case of Xanthogranulomatous Cholecystitis Associated with Mirizzi Syndrome
Abstract
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Xanthogranulomatous cholecystitis is an uncommon benign inflammatory disease of the gallbladder characterized histopathologically by extensive lipid-containing histiocytes. It has been usually mistaken for gallbladder cancer due to diffuse wall thickening of gallbladder with peripheral infiltration radiographically. Xanthogranulomatous cholecystitis has been reported to combine cholelithiasis frequently. A 59-year-old man was admitted with jaundice and right upper quadrant pain. By abdominal ultrasonogram, computed tomography scan, cholangiogram, and repeated biopsy, his case was diagnosed as xanthogranulomatous cholecystitis associated with Mirizzi syndrome. An exploratory laparatomy was performed. On operation, the gallbladder wall was irregularly markedly thickened and multiple stones existed in the gallbladder. The largest one (2 x 1.5 x 1.5 cm) of these stones was impacted in necrotic defect site between gallbladder wall and common hepatic duct wall, and it partially obstructed (80%) the common hepatic duct. Partial cholecystectomy with T-tube drainage was performed. Postoperatively, we diagnosed this case as xanthogranulomatous cholecystitis associated with Mirizzi syndrome.