Cutaneous Hydration Effect of Moisturizers: Urea , Hydration Base , Petrolatum

Kang, Ho Jung; Hahm, Jeong Hee

Abstract

BACKGROUND: Moisturize's were thought to increase the hydration of the outer layer of the epidermis. During recent years, new noninvasive methods for assessment of skin hydration have become available.
OBJECTIVE
The purpose of this study was to evaluat and compare the cutaneous hydration effect of three moisturizers (hydrophilic base, urea and petrolatum) in healthy females with dry leg skin.
METHODS
The regression method was applied for evaluating and comparing the effect of moisturizers. The hydration state was evaluated by Skicon-200(R) and skin dryness was evaluated by Biosit's method.
RESULTS
Three moisturizers improved the dry skin condition for the treatment period and for the 10 day regression period. Improvement of the hydrophilic base treated site continued for 20 days during the regression period and superior to petrolatum treated site.
CONCLUSION
Three moisturizers improve the stratum corneum hydration state significantly and its improvement has been continued for about 14days after treatment. Hydrophilic base moisturizers showed a better effect than petrolatum based ones.