Korean J Dermatol.  1997 Jun;35(3):556-560.

A Case of Erythema Nodosum-like leukemia cutis

• Kim JW
• Yoon YM
• Kim TH
• Kim DS
• Kim SW

Abstract

We have encountered a rare case of erythema nodosum-like leukemia cutis associated with acute myelocytic leukemia(AML) in a 57-year-old male. He was in good health until about 2 weeks prior to admission, when the systemic symptoms of high fever, anorexia, general weakness and malaise, and subcutaneous nodules developed. The nodules were multiple, red and noted bilaterally on the pretibial areas. Histological findings of his skin lesions showed diffuse cellular infiltrates intermingled with leukemic cells predominantly involving the adipose tissues. The cells displayed negative stainirig to antibodies CD3 and CD20, but positive staining to LCA. The diagnosis of AML(M4) was made by blood and bone marrow studies. He had a rapid downhill course and was discharged after 2 weeks of admission, with no anti-cancer chemotherapy.

Keyword

Acute myelocytic leukemia; Erythema nodosum-like lesion

MeSH Terms

Anorexia
Antibodies
Bone Marrow
Diagnosis
Drug Therapy
Erythema*
Fever
Humans
Leukemia*
Leukemia, Myeloid, Acute
Male
Middle Aged
Skin
Antibodies