Korean J Dermatol.  1999 Aug;37(8):1100-1103.

A Case of Subcutaneous Panniculitic T-cell Lymphoma

• Kim SW
• Jang HC
• Kim DS

Abstract

A 41-year-old woman was presented with dusky-red colored, multiple subcutaneous infiltrative plaques of varing size(3-15cm in diameter) on both lower legs, the right ankle and the left antecubital area for about 6 months. Although she complained of sensory disturbance on the skin lesions which led to suspect lepromatous leprosy, there was no evidence of leprosy. Skin biopsy specimens showed dense small and medium-sized atypical lymphoid cell infiltrates in the subcutis, with a mixed septal and lobular pattern and a few scattered hemophagocytic cells. Angioinvasion and angiodestruction were seen in the focal area of deep dermis. Immunohistochemistry displayed positive reactions to LCA, CD3 and UCHL-1, but negative to CD20 and CD30. EBV antigen on the tissue was positive. The clinicopathologic features were consistent with subcutaneous panniculitic T-cell lymphoma.

Keyword

Subcutaneous panniculitic; T-cell lymphoma

MeSH Terms

Adult
Ankle
Biopsy
Dermis
Female
Herpesvirus 4, Human
Humans
Immunohistochemistry
Leg
Leprosy
Leprosy, Lepromatous
Lymphocytes
Lymphoma, T-Cell*
Skin
T-Lymphocytes*