Korean J Dermatol.  2007 Aug;45(8):836-839.

A Case of Norwegian Scabies in Patient with Acute Myeloid Leukemia Associated Graft-versus-host Disease

Affiliations
  • 1Department of Dermatology, Chonnam National University Medical School, Gwangiu, Korea. schul@chonnam.ac.kr
  • 2Department of Pediatrics, Chonnam National University Medical School, Gwangiu, Korea.

Abstract

Norwegian scabies is a crusted non-itchy rash caused by massive infestation with the mite Sarcoptes scabiei. It is usually associated with immunosuppression or neurologic impairment, although it has rarely been reported in normal persons. We report a case of Norwegian scabies in 6-year old girl with acute myeloid leukemia associated graft-versus-host disease. The lesion showed pruritic, hyperkeratotic scaly plaques and fissures on the entire body. Application of a mineral oil preparation from hyperkeratotic areas showed numerous scabies mites. Treatment with 10% crotamiton cream for two weeks resulted in marked regression of the skin lesions, but finally she died of sepsis due to deterioration of her systemic conditions.

Keyword

Acute myeloid leukemia; Graft-versus-host disease; Norwegian scabies

MeSH Terms

Child
Exanthema
Female
Graft vs Host Disease*
Humans
Immunosuppression
Leukemia, Myeloid, Acute*
Mineral Oil
Mites
Sarcoptes scabiei
Scabies*
Sepsis
Skin
Mineral Oil
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