Korean J Dermatol.
2007 Oct;45(10):1074-1077.
A Case of Neurotized Nevus with Sclerotic Fibroma-like Change
- Affiliations
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- 1Department of Dermatology, College of Medicine, Ewha Womans University, Seoul, Korea. JHHAHM@mm.ewha.ac.kr
Abstract
- We report a case of neurotized nevus with a sclerotic fibroma-like change in a 60-year-old female patient, who presented with a brown colored pedunculated nodule on the upper quadrant of the abdomen. The skin biopsy revealed a well-circumscribed, non-encapsulated nodule in the reticular dermis, which consisted of hypocellular hyalinized collagen bundles separated by clefts mixed with nevus cells. Nevus cells are small with a spindle appearance and contain Meissner corpuscle-like structures called nevic corpuscles. We suggest that a sclerotic fibroma-like change is an evolutionary end-point of a pre-existing lesion. This is supported further by the fact that neuroid change in the intradermal nevus represents the end stage of maturation of melanocytes of the nevi.
