Korean J Dermatol.  2008 Feb;46(2):285-288.

Macular Amyloidosis Presented as Depressed Patches on the Face

Affiliations
  • 1Department of Dermatology, Inha University School of Medicine, Incheon, Korea. jshin@inha.ac.kr

Abstract

We report a 58-year-old woman with an unusual clinical presentation of macular amyloidosis who had erythematous depressed patches without rippled pattern. The lesion was localized involving only the face: both lateral sides of the forehead. A skin biopsy revealed amyloid deposits on the papillay dermis. An immunofluorescence study demonstrated positivity for IgA in the amyloid deposits. The skin lesion of this patient could easily be confused with chronic cutaneous lupus erythematousus and the immunofluorescence finding suggests the possibility of specific immunoglobulin absorption of amyloid deposits.

Keyword

Depressed patch; Face; Macular amyloidosis

MeSH Terms

Absorption
Amyloid
Amyloidosis
Biopsy
Dermis
Female
Fluorescent Antibody Technique
Forehead
Humans
Immunoglobulin A
Immunoglobulins
Middle Aged
Plaque, Amyloid
Skin
Amyloid
Immunoglobulin A
Immunoglobulins
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