Korean J Dermatol.  2008 Feb;46(2):272-277.

Six Cases of Congenital Tufted Angioma

Affiliations
  • 1Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. seokjong@knu.ac.kr
  • 2Department of Plastic Surgery, Kyungpook National University School of Medicine, Daegu, Korea.
  • 3Department of Pathology, Kyungpook National University School of Medicine, Daegu, Korea.
  • 4Department of Pathology, Fatima Hospital, Daegu, Korea.

Abstract

Tufted angioma is a rare slowly progressive vascular tumor, characterized by histopathologic findings of numerous angiomatous lobules of "cannonball" appearance within the dermis. It affects children but occurs infrequently at birth. It appears as a clinical imitator of hemangioma of infancy (HOI), so it needs to be differentiated from HOI. Clinically, lesions most often present as red to purple, indurated or nodular plaque, and are usually located on the neck, upper trunk or proximal limb. We report six cases of tufted angioma of congenital onset. We undertook immunohistochemical study using CD31, D2-40 and GLUT1 to rule out other vascular tumors or malformations, particularly HOI. These cases may demonstrate the keys of differential diagnosis between HOI and tufted angioma, which share common features clinically and rarely histopathologically.

Keyword

Congenital tufted angioma; Differential diagnosis; Hemangioma of infancy

MeSH Terms

Child
Dermis
Diagnosis, Differential
Extremities
Hemangioma
Humans
Iodine Compounds
Neck
Parturition
Skin Neoplasms
Hemangioma
Iodine Compounds
Skin Neoplasms
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