Korean J Dermatol.
2010 Mar;48(3):220-227.
Five Cases of Glomuvenous Malformations
- Affiliations
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- 1Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. seokjong@knu.ac.kr
- 2Department of Plastic Surgery, Kyungpook National University School of Medicine, Daegu, Korea.
- 3Department of Pathology, Kyungpook National University School of Medicine, Daegu, Korea.
- 4Department of Radiology, Kyungpook National University School of Medicine, Daegu, Korea.
Abstract
- Glomuvenous malformation (GVM), an uncommon variant of venous malformation (VM), reveals dilated venous channels lined by variable amounts of glomus cells histopathologically. It appears as compressible blue or blue-purple nodules or plaque(s), sometimes showing a familial tendency. GVM usually involves only the superficial layer of the cutis or subcutaneous tissue, unlike VM, which frequently involves deeper tissue. Although GVM shares features of VM and glomus tumor, their clinicopathological and/or genetic features are sufficiently distinctive to enable a differential diagnosis, which is important for management decisions. Herein, we report five patients who showed a large confluent patch or several scattered patches composed of tender bluish blebs. Two patients among them were siblings. Histopathological and immunohistochemical examinations confirmed GVM.
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