Korean J Community Nutr.  2003 Jun;8(3):349-355.

Development of Dietary Supplement for the Growth and Exercise Performance Improvement

• Yoon SW
• Jung EH
• Yang DS
• Lee HS
• Yoon YS

Abstract

We developed a dietary supplement using natural herbs and nutrients for the growth and exercise performance improvement. It called 50-22 supplement containing distilled extracts of natural herbs to remove bitterness and the addition of Vitamin B1, B6, Ca and xylitol. We investigated on the effect of 10-22 supplementation on the maximal exercise performance, IGF-1 (insulin like growth factor-1) concentration and antioxidant activity in SD rat model. In result, JR-22 supplement group was better than control group about 10% in exercise performance test and increased about 63% of IGF-1 concentration in blood. In addition, the oxidative damage induced by exercise was reduced by JR-22 supplementation. Therefore, we suggested that 50-22 supplementation enhanced effectively exercise performance and IGF-1 concentration and reduced to oxidative stress in muscles. Also, we analysed biochemical factors in blood for the safety of JR-22 supplement. We known that there is no change of blood lactic acid, ammonia, inorganic phosphorous ion and creatine kinase activity.

Keyword

growth; IGF-1; antioxidant activity; exercise performance

MeSH Terms

Ammonia
Creatine Kinase
Dietary Supplements*
Insulin-Like Growth Factor I
Lactic Acid
Models, Animal
Muscles
Oxidative Stress
Thiamine
Xylitol
Ammonia
Creatine Kinase
Insulin-Like Growth Factor I
Lactic Acid
Thiamine
Xylitol