Korean J Blood Transfus.  2001 Dec;12(2):257-261.

A Case of Anti-Xga Antibody

Affiliations
  • 1Departments of Clinical Pathology, Hallym University College of Medicine, Korea.
  • 2Departments of General Surgery, Hallym University College of Medicine, Korea.
  • 3Departments of Clinical Pathology, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Anti-Xga is a rarely occurring antibody, and only two cases with this antibody have been reported in Koreans. We describe here another example of anti-Xga which was detected in a 47-year-old male. The patient suffered from burn injury on the 20% of body surface area, acute renal failure, and ulcer bleeding. Unexpected antibody identification test demonstrated anti-Xga, which was reactive only by antiglobulin phase, and the reaction disappeared after the treatment with bromelin. The red cell phenotype of this patient was Xg(a-). Fourteen units of packed red blood cell were transfused without any adverse reactions. It has an important clinical concern in safe transfusion practice to determine the specificity and the clinical significance of blood group alloantibodies.

Keyword

anti-Xga; unexpected antibody; specificity; transfusion

MeSH Terms

Acute Kidney Injury
Body Surface Area
Bromelains
Burns
Erythrocytes
Hemorrhage
Humans
Isoantibodies
Male
Middle Aged
Phenotype
Sensitivity and Specificity
Ulcer
Bromelains
Isoantibodies
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