Korean J Biol Psychiatry.
2011 May;18(2):55-60.
Recent Neuroimaging Study in Schizophrenia
- Affiliations
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- 1Department of Psychiatry, Eulji University College of Medicine, Daejeon, Korea. bumseok.jeong@gmail.com
- 2Department of Psychiatry, Daejeon St. Mary's Hospital, Catholic University of Korea, Daejeon, Korea.
Abstract
- Neuroimaging studies in schizophrenia have remarkably increased and provided some clues to understand its pathophysiology. Here, we reviewed the neuroimaging, studies including volume analysis, functional magnetic resonance imaging (MRI) and diffusion tensor imaging, and findings in both early stage schizophrenia and high-risk group. The reviewed studies suggested that the brain with schizophrenia showed both regional deficits and dysconnectivity of neural circuit in the first episode, even high-risk group as well as chronic schizophrenia. Multimodal neuroimaging or combined approach with genetic, electro- or magneto-encephalographic data could provide promising results to understand schizophrenia in the near future.