Korean J Asthma Allergy Clin Immunol.
2007 Mar;27(1):70-73.
Occupational Asthma due to Styrene and Toluene Diisocyanate
Abstract
- Styrene, a common solvent and volatile organic compound (VOC), is widely used in the factories of plastics, resins, insulators, coatings, and paints. While toluene diisocyanate (TDI) is a well-known causative agent of asthma, styrene has been rarely reported to cause occupational asthma (OA). We report a 50-year-old repairman with OA due to both styrene and TDI in whose job was filling cracks and flattening the surface of vehicles with styrene-containing plaster's putty, followed by spray painting. He suffered from cough, dyspnea durings the work with putty. Hepresented with a 2-year history of asthma and allergic rhinitis. The level of serum total IgE and sputum eosinophils were 2,878 IU/L and 63%, respectively. The methacholine challenge test was positive (PC20 0.59 mg/mL). The bronchoprovacation tests with TDI and styrene showed early and dual responses, respectively. Currently, he is in well- controlled state with the use of a combination of inhaled corticosteroid and long acting beta2-agonist after the avoidance of the causative agents.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A case of occupational asthma with systemic illness due to toluene diisocyanate and diphenylmethane diisocyanate
- A Case of Chromium- and Toluene Diisocyanate-Induced Asthma
- A case of bronchial asthma induced by toluene diisocyanate(TDI) in the external environment
- A status of occupational asthma in Korea through the cases reported to the Occupational Asthma Surveillance Center
- Significant changes of bronchial responsiveness to methacholine after early asthmatic reaction to toluene diisocyanate (TDI) in a TDI-sensitive asthmatic worker
