Korean J Asthma Allergy Clin Immunol.
2009 Sep;29(3):204-207.
A Case of Anaphylaxis Induced by Polysorbate 80 in Parenteral Multivitamin
Abstract
- Polysorbates including polysorbate 80 is a solubilizing agents widely used in cosmetics and medical preparations such as vitamins, vaccines and anticancer agents. A 64- year-old woman experienced generalized urticaria, angioedema, hypotension and loss of consciousness during intravenous administration of aminoacid fluid with multi-vitamin. Skin prick test with multivitamin and its 15 ingredients including polysorbate 80 showed a strong positive reaction to polysorbate 80 only. Based on her symptoms and the result of skin prick test, we confirmed that she had polysorbate 80-induced anaphylaxis.
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