Korean J Anesthesiol.  2009 Feb;56(2):195-199. 10.4097/kjae.2009.56.2.195.

Delayed recovery of neuromuscular blockade by rocuronium in a hypothermic patient during a laparoscopic procedure: A case report

• Ryu JK
• Lee BJ
• Yang KA
• Jung O

• KMID: 2299317
• DOI: http://doi.org/10.4097/kjae.2009.56.2.195

Abstract

Perioperative hypothermia can occur frequently and lead to various complications. Laparoscopic procedures do not require a large incision or exposure of the viscera, but a prolonged and high pressure procedure can lead to unexpected hypothermia. Hypothermia prolongs the time-course of non-depolarizing neuromuscular blocking agents by reducing the plasma clearance significantly. Rocuronium, a new aminosteroidal neuromuscular blocking agent, can be influenced by reductions in plasma clearance and prolong the duration of action. Therefore, patients must receive ventilator care in the ICU. Aggressive measures were taken for hypothermia, and the patient was discharged without any complications. We report a case of delayed of neuromuscular blockade by rocuronium in a hypothermic patient during a laparoscopic procedure with a brief review of literatures.

Keyword

Hypothermia; Laparoscopy; Rocuronium

MeSH Terms

Androstanols
Humans
Hypothermia
Laparoscopy
Neuromuscular Blockade
Neuromuscular Blocking Agents
Plasma
Ventilators, Mechanical
Viscera
Androstanols
Neuromuscular Blocking Agents