Korean J Anesthesiol.  1997 Dec;33(6):1129-1133. 10.4097/kjae.1997.33.6.1129.

Caudal Epidural Morphine for Postoperative Analgesia in Children

• Han CS
• Choi IS
• Kim IH
• Kim YJ
• Kim CS
• Ahn KR

• KMID: 2299261
• DOI: http://doi.org/10.4097/kjae.1997.33.6.1129

Abstract

BACKGROUND: The use of caudal morphine for postoperative analgesia has been increased in popularity since 1981. The purpose of this study was to compare the effect of analgesia and incidence of side effects of a mepivacaine-morphine mixture with mepivacaine alone.
METHODS
Forty patients were randomly divided into two groups. In group 1, caudal block was performed with 1% mepivacaine 1 ml/kg alone. In group 2, caudal block was performed with 1% mepivacaine 1ml/kg-morphine 0.03 mg/kg mixture. Postoperative five-point pain scores and side effects were measured.
RESULTS
There were no significant differences in sedation dose, incidence of side effects and supplemental analgesics. Pain scores were significantly lower at postoperative 2 and 3 hours in mepivacaine-morphine mixture group.
CONCLUSIONS
Caudal epidural mepivacaine-morphine (0.03 mg/kg) mixture is effective in children for control of postoperative pain without significant side effects.

Keyword

Analgesia, postoperative; Analgesics, morphine; Anesthetics, local, mepivacaine; Anesthesia, pediatric, caudal

MeSH Terms

Analgesia*
Analgesics
Child*
Humans
Incidence
Mepivacaine
Morphine*
Pain, Postoperative
Analgesics
Mepivacaine
Morphine