Influencing Factors on Pharmacologic Erectile Response in Patients with Erectile Dysfunction

Chung, Woo Sik

Abstract

PURPOSE: We examined the predictable determinants affecting satisfactory rigidity induced by PGE1 in patients with dysfunction.
MATERIALS AND METHODS
Two hundred and sixty eight consecutive impotent patients entered the study. The pharmacologic erectile response to intracavernosal injection of PGE1 10 micro gram were analysed according to several factors which were patient's age, duration of impotent symptom, quality of residual erectile function, smoking and alcohol consumption history, and vascular risk factors of diabetes, hypertension, heart diseases and hypercholesterolemia.
RESULTS
There was a significant decrease of erectile response to PGE1 in patients having vascular risk factors (p<0.01). Patient's age and quality of residual erectile function had an significant effect on pharmacologic erectile response (p<0.05). Other factors such as impotent duration and smoking/alcohol consumption did not reach significant difference.
CONCLUSIONS
These data demonstrates that patient's age and their vascular risk factors have negative effect and residual erectile function has positive effect on the pharmacologic penile erection in patients with erectile dysfunction.