Korean J Androl.  2009 Aug;27(2):96-101.

The Adverse Effects of Cardiovascular Risk Factors on Lower Urinary Tract Symptoms and Erectile Function

Affiliations
  • 1Department of Urology, Chonnam National University Medical School, Gwangju, Korea. uropark@gmail.com

Abstract

PURPOSE: There are several reports about relationships between cardiovascular risk factors and lower urinary tract symptoms (LUTS). We investigated the effects of risk factors for vascular disease on LUTS and erectile function (ED).
MATERIALS AND METHODS
We prospectively analyzed 273 patients who had LUTS or ED. A self administered questionnaire of International Prostate Symptom Score (IPSS) and International Index of Erectile Function (IIEF) were given to patients. Cardiovascular risk factors including hypertension, smoking status, diabetes and dyslipidemia were determined in each patients.
RESULTS
Mean age was 60.5+/-9.4 years. Mean IPSS, IIEF and IIEF-EF score were 15.9+/-5.9, 30.1+/-15.4 and 17.35+/-9.0, respectively. There are statistically significant differences in the IPSS (p=0.047), IIEF (p=0.024) and IIEF-EF domain score (p=0.044) between men with no risk factors and men with one or more risk factors. IPSS, IIEF and IIEF-EF score were 11.5+/-6.4, 39.8+/-11.9 and 19.6+/-8.7 in men with no risk factor (n=94), 16.6+/-5.6, 28.4+/-15.0 and 15.1+/-9.3 in men with at least one risk factor (n=179). In men with one to four risk factors, the mean IPSS was 14.5+/-5.1 (n=63), 16.3+/-4.4 (n=45), 21.2+/-5.5 (n=43) and 26.5+/-3.5 (n=28)(p=0.001); the mean IIEF score was 31.4+/-14.2, 27.8+/-16.8, 22.5+/-14.1 and 19.0+/-9.9 (p=0.037); the mean IIEF-EF score was 17.1+/-8.9, 14.7+/-9.0, 10.9+/-9.7 and 8.8+/-4.5 (p=0.023), respectively.
CONCLUSIONS
Men with risk factors for vascular disease are more likely to have a higher IPSS and a lower IIEF and IIEF-EF score than men without risk factors. These results suggests that vascular disease of men is significantly related with the progression of LUTS and ED.

Keyword

Vascular diseases; Lower urinary tract symptoms; Erectile dysfunction

MeSH Terms

Dyslipidemias
Erectile Dysfunction
Humans
Hypertension
Lower Urinary Tract Symptoms
Male
Multiple Endocrine Neoplasia Type 1
Prospective Studies
Prostate
Surveys and Questionnaires
Risk Factors
Smoke
Smoking
Vascular Diseases
Smoke
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