Korean Circ J.  2000 Aug;30(8):1040-1044. 10.4070/kcj.2000.30.8.1040.

Initiation of Torsades de pointes by head-up tilt test in congenital long QT syndrome patient

• Jeon IS
• Cha TJ
• Kim KS
• Kim DW
• Kim KJ
• Kim SM
• Joo SJ
• Lee JW

• KMID: 2298034
• DOI: http://doi.org/10.4070/kcj.2000.30.8.1040

Abstract

Long QT syndrome is a cardiac disorder of repolarization which is characterized by elctrocardiographic abnormalities including prolonged QT interval, T-wave abnormalities and polymorphic ventricular tachycardia known as Torsades de Pointes. Its clinical manifestation are recurrent syncope, seizure, and sudden death. Recently,we experienced Torsades de Pointes(TdP) by head-up tilt test in 24 year-old female patient presenting recurrent syncope and long QT interval. Beta-blocker and left cervicothoracic sympathetic ganglionectomy were not effictive, then we tried mexiletine. After mexiletine medication, the QT interval was significantly shortened and there was no more syncope.

MeSH Terms

Death, Sudden
Female
Ganglionectomy
Humans
Long QT Syndrome*
Mexiletine
Seizures
Syncope
Tachycardia, Ventricular
Torsades de Pointes*
Young Adult
Mexiletine