J Rhinol.  2015 May;22(1):44-46. 10.18787/jr.2015.22.1.44.

Cholesterol Granuloma of Nasal Septum

• Koo SK
• Kim YJ
• Jung SH
• Son H

• KMID: 2297554
• DOI: http://doi.org/10.18787/jr.2015.22.1.44

Abstract

Cholesterol granulomas are inflammatory deposits commonly found in the mastoid antrum and air cells of temporal bone. They rarely occur in the nose. Here, we report an extremely rare case of cholesterol granuloma in the nasal septum, and include a short literature review. The clinical characteristics, pathology, and surgical treatment are also discussed.

Keyword

Cholesterol granuloma; Nasal septum

MeSH Terms

Cholesterol*
Granuloma*
Mastoid
Nasal Septum*
Nose
Pathology
Temporal Bone
Cholesterol

Figure

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  Fig. 1. Pre-operative nasal endoscopic findings. Right side of nasal cavity (A), left side of nasal cavity (B). The nasal septum is deviated to the left and the right inferior turbinate is hypertrophied. S: nasal septum, IT: inferior turbinate.

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  Fig. 2. CT images of patient. Coronal view (A), Axial view (B). These CT images show septal deviation and concave depression at left bony septum (Black arrow).

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  Fig. 3. Intraoperative finding. This figure shows bony septum (white arrow), right septal mucosa (black star), and cyst (black arrow). Cyst is filled with dark yellowish gel like material.

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  Fig. 4. Microphotograph showing foci of previous hemorrhage and deposition of hemosiderin pigments in the stroma of a nasal septal cyst (H-E stain, ×400).

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  Fig. 5. Microphotograph showing cholesterol clefts and associated foreign body giant cells in the fibrous stroma of a nasal septal cyst (H-E stain, ×100).

Reference

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