Korean J Urol.  2006 Nov;47(11):1139-1143. 10.4111/kju.2006.47.11.1139.

Laparoscopic Radical Nephrectomy for T2 Renal Cell Carcinomas

• Kim JS
• Kwon TG
• Kim BW

• KMID: 2294269
• DOI: http://doi.org/10.4111/kju.2006.47.11.1139

Abstract

Purpose
A laparoscopic radical nephrectomy (LRN) has emerged as the standard care in appropriate candidates with stage T1 renal tumors (7cm or less). We extended our experience of LRN to stage T2 renal tumors (greater than 7cm), and compared the results with those of LRN for stage T1 renal tumors, as well as with those of an open radical nephrectomy (ORN) for stage T2 renal tumors.
Materials and Methods
Between January 2001 and December 2004, a total of 67 patients, who underwent LRN for renal cell carcinomas, were retrospectively subdivided into the LRNT1 (n=48, tumor size7cm) groups. The surgical outcomes and perioperative morbidities were retrospectively evaluated. Also, the results of the LRNT2 group were compared with those of the open radical nephrectomy T2 group (ORNT2, n=29).
Results
Compared with the LRNT1 group, the LRNT2 group only had larger tumors, but comparable operation time, blood loss, variation in the creatinine value (Cr), analgesics requirements, time to ambulate and diet, hospital stay and complication rates. The tumor sizes were similar in the two groups (p=0.260). However, the LRNT2 group had shorter operation time (p=0.039), lesser blood loss (p=0.044), Cr (p=0.027), analgesic requirements (p<0.001) and time to ambulation, diet and hospital stay (p<0.001, all).
Conclusions
A LRN for stage T2 renal tumors is feasible and efficacious. The surgical outcomes were comparable with those of a LRN for stage T1 tumors, with the advantages of decreased blood loss and more rapid recovery over that of an ORN for comparable tumors greater than 7cm in size.

Keyword

Laparoscopy; Nephrectomy; Carcinoma; renal cell

MeSH Terms

Analgesics
Carcinoma, Renal Cell*
Creatinine
Diet
Humans
Laparoscopy
Length of Stay
Nephrectomy*
Retrospective Studies
Walking
Analgesics
Creatinine

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