Urodynamic Evaluations According to Clinical Findings and Clinical Significance of Glycosylated Hemoglobin (HbA1C) in Patients with Diabetic Cystopathy

Choi, A Ram; Lee, Seung Ju; Lee, Ji Youl

Abstract

PURPOSE: In an effort to characterize the complex voiding dysfunction associated with symptomatic diabetic patients, the results of urodynamic studies of diabetic patients were retrospectively analyzed.
MATERIALS AND METHODS
We retrospectively reviewed the clinical information, laboratory findings and urodynamic data, of patients with diabetic cystopathy (DCP) (20 males and 40 females) between January 1997 and December 2001. The urodynamic findings were classified as detrusor instability (DI), impaired detrusor contractility (IDC), detrusor areflexia (DA) and normal detrusor contraction (ND).
RESULTS
The mean duration of diabetes in irritative symptom group (40%), combined symptom group (26.7%) and obstructive symptom group (33.3%) was 3.4 years, 8.3 years and 15.2 years, respectively (p<0.05). Of the 20 patients with serum HbA1C<7%, 15 were noted in the irritative symptom group. Of the 20 patients with serum HbA1C>or=7%, 17 were noted in the obstructive symptom group. The urodynamic findings of the 60 diabetic patients were distributed as follows: 22 (36.7%) detrusor instability, 20 (33.3%) impaired detrusor contractility, 16 (26.7%) detrusor areflexia and 2 (3.3%) normal detrusor contraction.
CONCLUSIONS
The shorter the duration of diabetes, the more predominant were the signs of irritative symptoms, whereas the longer the duration of diabetes, the more predominant were the obstructive voiding symptoms. The patients with serum HbA1C<7% mostly complained of irritative symptoms, but the patients with serum HbA1C>or=7% mostly complained of obstructive symptoms.