Korean J Urol.  1998 Nov;39(11):1065-1069.

Age-specific Reference Ranges for Prostate-specific Antigen from a Community-based Study

• Hong JH
• Chung TG
• Park M
• Lee J
• Kim T
• Chung JS
• Lee MS
• Ahn HJ

Abstract

PURPOSE: To analyze the relationship of age to serum prostate-specific antigen (PSA) levels among Koreans without clinically evident prostate cancer in a community-based study. MATERIALS AND METHOD: A total of 375 healthy men aged 50 to 79, residing in the small farming villages of Jeong-Eup county, Korea were examined with serum PSA(Hybritech Tandem-R) and digital rectal examination. One case of patient with prostate cancer was excluded.
RESULTS
The serum PSA concentration is correlated with patient age(In PSA=-1.56+0.0257 x Age, r=0.32, p-value<0.0001). The recommended age-specific reference ranges of serum PSA(95th percentile) for men aged 50-59 years is 0-2.80ng/m1; for 60-69 years,0-3.56ng/m1; and for 70-79 years, 0-4.57ng/m1.
CONCLUSIONS
The serum PSA concentration is correlated with patient age in Korean men and the age-specific PSA reference ranges for Korean are lower than those for Caucasian.

Keyword

Prostate-specific antigen; Age-specific reference range; Korean Prostatic neoplasms

MeSH Terms

Digital Rectal Examination
Humans
Jeollabuk-do
Korea
Male
Prostate-Specific Antigen*
Prostatic Neoplasms
Reference Values*
Prostate-Specific Antigen