J Gynecol Oncol.  2011 Jun;22(2):135-139. 10.3802/jgo.2011.22.2.135.

Pure choriocarcinoma of the ovary: a case report

• Lv L
• Yang K
• Wu H
• Lou J
• Peng Z

• KMID: 2288579
• DOI: http://doi.org/10.3802/jgo.2011.22.2.135

Abstract

Pure ovarian choriocarcinomas are extremely rare and aggressive tumors which are gestational or non-gestational in origin. Due to the rarity of the tumor, there is a lack of information on the clinicopathologic features, diagnosis, and treatment. We report a case of a pure ovarian choriocarcinoma, likely of non-gestational origin, treated by cytoreductive surgery in combination with post-operative chemotherapy. The patient was free of disease after a 12-month follow-up.

Keyword

Choriocarcinoma; Non-gestational; Ovary

MeSH Terms

Choriocarcinoma
Female
Follow-Up Studies
Humans
Ovary
Pregnancy

Figure

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  Fig. 1 Microscopic appearance of the tumor shows a pure choriocarcinoma with widespread necrosis (H&E, ×200).

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  Fig. 2 Supporting immunohistochemistry shows that the tumor is positive for β-human chorionic gonadotropin (A) and weakly positive for placental-like alkaline phosphatase (B) (×200).

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  Fig. 3 Decrease in serum β-human chorionic gonadotropin (hCG) levels after surgery and combination chemotherapy with etoposide, cisplatin and bleomycin. #number indicates the cycle number of chemotherapy.

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