Korean J Spine.  2011 Jun;8(2):125-128. 10.14245/kjs.2011.8.2.125.

Solitary Hemangioblastoma at the Filum Terminale: A Case Report and Review of Literature

Affiliations
  • 1Department of Neurosurgery, Seoul Wooridul Hospital, Seoul, Korea.
  • 2Department of Orthopaedic Surgery, Seoul Wooridul Hospital, Seoul, Korea. ultralex@wooridul.co.kr
  • 3Department of Pathology, Seoul Wooridul Hospital, Seoul, Korea.

Abstract

Spinal hemangioblastomas at the filum terminale are rare. Only a few reports present immunohistopathological features of spinal hemangioblastomas. A 55-year-old woman presented with sustained low back pain and intermittent numbness in both lower extremities. She already had a decompressive surgery for a left L5-S1 extraforaminal lesion 7 months ago. Her incidental mass lesion had been slightly enlarged for 7 months and concordant symptoms had also been prolonged. Her tumor was removed en bloc with a unilateral hemilaminotomy and bilateral decompression technique. The patient's symptoms improved immediately after the surgery. In immunohistochemical stains, the stromal cells were positive for inhibin-alpha, neuron specific enolase (NSE), and the endothelial cells were positive for CD31, CD34, and factor VIII related antigen in confirming the diagnosis of hemangioblastoma. We report a rare case of intradural extramedullary spinal hemangioblastoma at the filum terminale. Complete en bloc resection was achieved with no morbidity. The immunohistopathological staining include inhibin-alpha confirmed an accurate diagnosis of the hemangioblastoma distinguishing from other vascular tumors.

Keyword

Spinal hemangioblastoma; Filum terminale; Immunohistopathological stain
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