Korean J Spine.  2011 Jun;8(2):125-128. 10.14245/kjs.2011.8.2.125.

Solitary Hemangioblastoma at the Filum Terminale: A Case Report and Review of Literature

• Lee JH
• Kim JU
• Paeng SS
• Jang JS
• Lee SH

• KMID: 2288452
• DOI: http://doi.org/10.14245/kjs.2011.8.2.125

Abstract

Spinal hemangioblastomas at the filum terminale are rare. Only a few reports present immunohistopathological features of spinal hemangioblastomas. A 55-year-old woman presented with sustained low back pain and intermittent numbness in both lower extremities. She already had a decompressive surgery for a left L5-S1 extraforaminal lesion 7 months ago. Her incidental mass lesion had been slightly enlarged for 7 months and concordant symptoms had also been prolonged. Her tumor was removed en bloc with a unilateral hemilaminotomy and bilateral decompression technique. The patient's symptoms improved immediately after the surgery. In immunohistochemical stains, the stromal cells were positive for inhibin-alpha, neuron specific enolase (NSE), and the endothelial cells were positive for CD31, CD34, and factor VIII related antigen in confirming the diagnosis of hemangioblastoma. We report a rare case of intradural extramedullary spinal hemangioblastoma at the filum terminale. Complete en bloc resection was achieved with no morbidity. The immunohistopathological staining include inhibin-alpha confirmed an accurate diagnosis of the hemangioblastoma distinguishing from other vascular tumors.

Keyword

Spinal hemangioblastoma; Filum terminale; Immunohistopathological stain

MeSH Terms

Cauda Equina
Coloring Agents
Decompression
Endothelial Cells
Female
Hemangioblastoma
Humans
Hypesthesia
Low Back Pain
Lower Extremity
Middle Aged
Phosphopyruvate Hydratase
Stromal Cells
von Willebrand Factor
Coloring Agents
Phosphopyruvate Hydratase
von Willebrand Factor