J Clin Pathol Qual Control.  1999 Dec;21(2):349-353.

Evaluation of Automated Coagulation Analyser STA Compact

• Jeon H
• Lee YK
• Lee KH
• Park JY
• Cho HC

Abstract

BACKGROUND: STA Compact (Diagnostica Stago, Chausson, France) is an automated coagulation analyser capable of performing clotting assays as well as chromogenic and immunological assays on plasma samples. We evaluated the usefulness of the STA Compact for prothrombin time (PT) and activated partial thromboplastin time (aPTT) with clotting method.
METHODS
We evaluated within-day and between-day precisions of PT and aPTT tests using pooled normal plasma and two levels of control materials (Coag N and Coag P, Diagnostica Stago, Chausson, France). We compared STA Compact with another automated coagulation analyser, Fibrintimer A (Dade Behring, Marburg, Germany). The reference values of PT and aPTT by STA Compact were derived using the samples from hemostatically normal individuals.
RESULTS
The within-day coefficients of variation (CVs) were in the range of 1.63% to 4.34% for PT, and 2.21% to 2.99% for aPTT respectively. The between-day CVs were in the range of 1.93% to 4.0% for PT, and 0.64% to 5.05% for aPTT respectively. On the comparison study between STA Compact and Fibrintimer A, correlation coefficients (R) were 0.93 (P<0.01) for PT and 0.94 (P<0.01) for aPTT respectively. The reference ranges (mean+/-2SD) of PT were 11.7 to 13.9 seconds, and those of aPTT were 34.7 to 46.4 seconds.
CONCLUSIONS
STA Compact showed good precision and correlation with Fibrintimer A. We concluded that STA Compact would be a useful analyser for routine coagulation tests.

MeSH Terms

Partial Thromboplastin Time
Plasma
Prothrombin Time
Reference Values